منابع مشابه
Comparative Plasma Lipidome between Human and Cynomolgus Monkey: Are Plasma Polar Lipids Good Biomarkers for Diabetic Monkeys?
BACKGROUND Non-human primates (NHP) are now being considered as models for investigating human metabolic diseases including diabetes. Analyses of cholesterol and triglycerides in plasma derived from NHPs can easily be achieved using methods employed in humans. Information pertaining to other lipid species in monkey plasma, however, is lacking and requires comprehensive experimental analysis. ...
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The influence of diet on cardiovascular disease (CVD) risk has long been a question of interest in the scientific community. The Seven Countries Study, established in 1958 by Ancel Keys, first suggested a link between the local diet and a reduction in CVD prevalence and death in Mediterranean populations (1). The “Mediterranean diet,” as described at the time, was notable in that a higher propo...
متن کاملAnimal cell cytokinesis: The role of dynamic changes in the plasma membrane proteome and lipidome.
In animal cells, cytokinesis is characterised by the formation of the mitotic spindle that signals the assembly of an actomyosin ring between the spindle poles. Contraction of this ring drives ingression of the cleavage furrow, and culminates in the formation of a thin intercellular bridge between the daughter cells. At the centre of this bridge is the midbody, which is thought both to provide ...
متن کاملHuman Tear Fluid Lipidome: From Composition to Function
We have explored human aqueous tear fluid lipidome with an emphasis to identify the major lipids. We also address the physiological significance of the lipidome. The tears were analysed using thin layer chromatographic, enzymatic and mass spectrometric techniques. To emphasize the physiological aspect of the lipidome, we modelled the spreading of the non-polar tear fluid lipids at air-water int...
متن کاملDiet, cancer, and the lipidome.
The potential for dietary fat to interfere with the development of breast cancer by delaying its occurrence makes the identification of defined molecules a mandatory step in cancer prevention. In order to circumvent the limitations and/or bias of dietary exposure assessment tools, biomarkers of past lipid intake such as the fatty acid composition of white adipose tissue have been used. When con...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2011
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmra1104901